Jesse Lambert grew up in rural New Hampshire and New York City. He received a BFA from Cooper Union and a MFA in Painting from Hunter College. He attended the Skowhegan School of Painting and Sculpture.

Jesse has exhibited his work at Front Room Gallery, NYC; Teckningsmuseet, Laholm, Sweden; Ningyo Editions, Watertown, MA; White Columns, NYC; Joseloff Gallery, Hartford, CT; Matter Gallery, Portland, ME; Klaus Von Nichtssagend Gallery, NYC; Miller Block Gallery, Boston, MA and other venues.

His exhibitions have been reviewed on Hyperallergic, artnet.com, in the New York Times, the Boston Globe, the Brooklyn Rail, the Yale Daily News and the Aravot Daily, Yerevan, Armenia.

Jesse has published his comics in Hyperallergic and contributed to the nonfiction comics anthologies COVID Chronicles, published by Graphic Mundi, American Cult, published by Paper Rocket Comics/Silver Sprocket, and Clayton: Godfather of the Lower East Side – A Documentary, published by Permuted Press. He will be included in Rescue Party: A Graphic Anthology of COVID Lockdown, coming in June 2024 from Knopf Doubleday. He has exhibited his comics at the independent comics festivals MoCCA, SPX, The Nonfiction Comics Festival, MICE, the Queens Zine Fest, The Brooklyn Independent Comics Showcase, and at the Jersey Art Book Fair.

He received a New Work Grant from the Queens Council on the Arts and a NYFA City Artists Corps Grant in 2021. In 2020, he was a finalist for the Creative Capital Awards.

He lives in Jackson Heights, Queens, NY, and maintains a studio in East Williamsburg, Brooklyn.